The Alarming Truths About GMO (7 mn. - 13 May 2013)
Research Reveals Previously Unknown Pathway by which Glyphosate Wrecks Health
by Dr. Mercola, 14 May 2013 (Click here for article in full.)
The more we learn about genetically engineered (GE) foods, the clearer the dangers become. I’ve warned you of the potential dangers of GE foods for many years now, as I was convinced that the artificial combining of plants with genes from wildly different kingdoms is bound to cause problems.
As the years roll on, such suspicions are becoming increasingly validated. In recent weeks, we’ve not only learned that GE corn is in no way comparable to natural corn in terms of nutrition, we’re also discovering the ramifications of dousing our crops with large amounts of glyphosate — the active ingredient in Monsanto’s broad-spectrum herbicide Roundup.
GE crops are far more contaminated with glyphosate than conventional crops, courtesy of the fact that they’re engineered to withstand extremely high levels of Roundup without perishing along with the weed.
A new peer-reviewed report authored by Anthony Samsel, a retired science consultant, and a long time contributor to the Mercola.com Vital Votes Forum and Dr. Stephanie Seneff, a research scientist at the Massachusetts Institute of Technology (MIT) has fortunately received quite a bit of mainstream media attention.
Their findings, along with the development of another breed of “gene silencing” crops, makes the need for labeling all the more urgent, and the advice to buy certified organic all the more valid.
How Glyphosate Worsens Modern Diseases
While Monsanto insists that Roundup is safe and “minimally toxic” to humans, Samsel and Seneff's research tells a different story altogether. Their report, published in the journal Entropy,1 argues that glyphosate residues, found in most commonly consumed foods in the Western diet courtesy of GE sugar, corn, soy and wheat, “enhance the damaging effects of other food-borne chemical residues and toxins in the environment to disrupt normal body functions and induce disease.” According to the authors:
"Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body.”
The main finding of the report is that glyphosate inhibits cytochrome P450 (CYP) enzymes, a large and diverse group of enzymes that catalyze the oxidation of organic substances. This, the authors state, is “an overlooked component of its toxicity to mammals.”
One of the functions of CYP enzymes is to detoxify xenobiotics—chemical compounds found in a living organism that are not normally produced or consumed by the organism in question. By limiting the ability of these enzymes to detoxify foreign chemical compounds, glyphosate enhances the damaging effects of those chemicals and environmental toxins you may be exposed to.
Dr. Stephanie Seneff has been conducting research at MIT for over three decades. She also has an undergraduate degree in biology from MIT and a minor in food and nutrition, and I have previously interviewed her about her groundbreaking insights into the critical importance of sulfur in human health. Not surprisingly, this latest research also touches on sulfur, and how it is affected by glyphosate from food.
“Here, we show how interference with CYP enzymes acts synergistically with disruption of the biosynthesis of aromatic amino acids by gut bacteria, as well as impairment in serum sulfate transport,” the authors write.
“Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease.
We explain the documented effects of glyphosate and its ability to induce disease, and we show that glyphosate is the 'textbook example' of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins.”
The Link Between Your Gut and the Toxicity of Glyphosate
The impact of gut bacteria on your health is becoming increasingly more well-understood and widely known. And here, we see how your gut bacteria once again play a crucial role in explaining why and how glyphosate causes health problems in both animals and humans. The authors explain:
“Glyphosate’s claimed mechanism of action in plants is the disruption of the shikimate pathway, which is involved with the synthesis of the essential aromatic amino acids, phenylalanine, tyrosine, and tryptophan. The currently accepted dogma is that glyphosate is not harmful to humans or to any mammals because the shikimate pathway is absent in all animals.
However, this pathway is present in gut bacteria, which play an important and heretofore largely overlooked role in human physiology through an integrated biosemiotic relationship with the human host. In addition to aiding digestion, the gut microbiota synthesize vitamins, detoxify xenobiotics, and participitate in immune system homeostasis and gastrointestinal tract permeability. Furthermore, dietary factors modulate the microbial composition of the gut.”
As noted in the report, incidences of inflammatory bowel diseases and food allergies have substantially increased over the past decade. According to a recent CDC survey, one in 20 children now suffer from food allergies2 — a 50 percent increase from the late 1990’s. Incidence of eczema and other skin allergies have risen by 69 percent and now affect one in eight kids. Samsel and Seneff argue it is reasonable to suspect that glyphosate’s impact on gut bacteria may be contributing to these diseases and conditions. They point out that:
“...Our systematic search of the literature has led us to the realization that many of the health problems that appear to be associated with a Western diet could be explained by biological disruptions that have already been attributed to glyphosate.
These include digestive issues, obesity, autism, Alzheimer’s disease, depression, Parkinson’s disease, liver diseases, and cancer, among others. While many other environmental toxins obviously also contribute to these diseases and conditions, we believe that glyphosate may be the most significant environmental toxin, mainly because it is pervasive and it is often handled carelessly due to its perceived nontoxicity.
...[T]he recent alarming increase in all of these health issues can be traced back to a combination of gut dysbiosis, impaired sulfate transport, and suppression of the activity of the various members of the cytochrome P450 (CYP) family of enzymes.” ...